The 50-year-old has revealed her mental health troubles have affected her relationships with her family members, reports variety.com.
"The fact that there's such stigma about mental illness means that the illness doesn't get talked about. It's not easy for families of mentally ill people. We can be difficult," Sinead O'Connor said.
A video was posted online last month in which O'Connor broke down as she discussed her personal troubles and suicidal thoughts.
Reflecting on the incident, she said: "I have been thinking about it for a year, actually. I thought about it for a year before I did it."